NCI CANCERLIT^® Search: Urothelial Tract Cancer - September 2001

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Ultima Vez Modificado: 1 de noviembre del 2001

[Post-surgical spindle cell nodule in kidney pelvis]
Adenoma of the posterior urethra: 131 case report.
The treatment of primary urethral carcinoma--the dilemmas of a rare condition: experience with partial urethrectomy and adjuvant chemotherapy.
[Laparoscopy-assisted total nephroureterectomy for renal pelvic and/or lower ureteral cancer]
Renal pelvic carcinoma of horseshoe kidney caused systemic metastasis by implantation in prostate.
[Transitional cell carcinoma on ureteral stump after nephrectomy for pyonephrosis]

CancerMail from the National Cancer Institute

1
UI - 21243934
AU - Jimenez Calvo J; Guarch Troyas R; Lozano Urunuela F; de Pablo Cardenas A; Pinos Paul M; Jimenez Aristu J; Montesino Semper M; Santiago Gonzalez de Garibay A
TI - [Post-surgical spindle cell nodule in kidney pelvis]
SO - Actas Urol Esp 2001 Feb;25(2):119-21
AD - Servicio de Urologia, Servicio de Anatomia Patologica, Hospital Virgen del Camino, Pamplona, Navarra.
INTRODUCTION: The postoperative spindle cell nodule of the urinary tract is a being proliferative lesion similar to sarcoma in the microscopic exam. We present a case of modulein renal pelvis location. CASE: A woman presenting a stag horn lithiasis in left kidney was treated by LOC and percutaneous nephroscopy. Because of the large size of the stone a second intervention was required four weeks later. Then we discovered a 2 cm exophytic lesion in renal pelvis and removed it easily with a forceps. DISCUSSION: This kind lesion belong to the group of iatrogenic inflammatory pseudotumours, which are secondary to an injury that leads to a tissular repairing response. Differential diagnostic includes sarcomas. CONCLUSION: It is important that Urology and pathology specialist think of this tumour in patients having a recent surgical intervention. A mistake in the diagnosis would lead us to an unnecessary radical surgery.

2
UI - 21228144
AU - Mi ZG; Yang XF; Liang XZ; Liu HY; Liu SY; Zhang H; Wang DW; Liu C
TI - Adenoma of the posterior urethra: 131 case report.
SO - Asian J Androl 2001 Mar;3(1):67-70
AD - Department of Urology, The First Affiliated Hospital, Shanxi Medical University, Taiyuan, China.
AIM: A case-report on adenoma of the posterior urethra. METHODS: In 131 cases of adenoma of the posterior urethra, aged 17-79 (mean: 36.4) years, a detailed medical history was taken and urinalysis, urethroscopy, and prostatic specific antigen (PSA) immunohistochemical staining were performed. They were then treated with transurethral resection (TUR) or transurethral electric coagulation (TUEC). RESULTS: Hemospermia occurred in 51% of the cases, hematuria in 38%, blood overflow from the urethral orifice in 6%, and dysuria in 5%. The position of the tumor was at or around the verumontanum. The appearance of the tumor was similar to those of a papilla, a villus, a dactyl or polyp, or simply an engorgement. The tumor contained glandular alveoli and adeno-epithelial cells. PSA immunohistochemistry was positive in the cytoplasm and nucleus of the adeno-epithelial cell. One hundred and tweenty-nine cases were cured after TUR or TUEC, while 2 patients recurred and were operated again. CONCLUSION: Adenoma of the posterior urethra is a common cause of hemospermia and hematuria in young men. Urethroscopic examination and biopsy are the principal diagnostic measures. TUR or TUEC are believed to be the treatment of choice with a short-term recurrence rate of around 1. 5%.

3
UI - 21340670
AU - Hakenberg OW; Franke HJ; Froehner M; Wirth MP
TI - The treatment of primary urethral carcinoma--the dilemmas of a rare condition: experience with partial urethrectomy and adjuvant chemotherapy.
SO - Onkologie 2001 Feb;24(1):48-52
AD - Klinik und Poliklinik fur Urologie, Universitatsklinikum Carl-Gustav Carus, Dresden. hakenberg@debitel.net
BACKGROUND: Primary urethral carcinoma is a very rare condition, and no large-scale experience with such cases has been published. Treatment will therefore have to follow rules established for the treatment of similar conditions. PATIENTS: Six cases of primary urethral carcinoma (5 male, 1 female) who had been treated at our institution between 1995 and 1999 were retrospectively analyzed. In 3 male cases, a primary urothelial carcinoma of the distal urethra was treated by distal urethrectomy only. In 3 other cases with locally advanced tumors and/or lymph node metastases surgical treatment was followed by adjuvant cisplatinum-containing chemotherapy. RESULTS: In the 3 cases with distal urethral carcinoma, partial urethrectomy with preservation of the penis resulted in cure, with a follow-up of 12-71 months. In the cases with advanced disease, adjuvant chemotherapy after surgery has resulted in complete remissions in all 3 cases, with a follow-up of 4-47 months at present. CONCLUSIONS: In localized, noninvasive carcinoma of the distal male urethra, partial urethrectomy seems adequate and the avoidance of penile amputation justified. In advanced cases, after local excision and lymphadenectomy adjuvant chemotherapy which by necessity must follow the guidelines established for the treatment of other urothelial or squamous cell malignancies seems to be beneficial. Copyright 2001 S. Karger GmbH, Freiburg

4
UI - 21409373
AU - Mizoguchi H; Yano A; Hashimoto K; Ohkuchi T; Emoto A; Ohno H; Nasu N
TI - [Laparoscopy-assisted total nephroureterectomy for renal pelvic and/or lower ureteral cancer]
SO - Nippon Hinyokika Gakkai Zasshi 2001 Jul;92(5):554-9
AD - Department of Urology, Nakatsu Daiichi Hospital, Nakatsu, Japan.
PURPOSE: The usefulness of laparoscopy-assisted total nephroureterectomy for patients with renal pelvic and lower ureteral cancer is evaluated. MATERIAL: Seven patients with renal pelvic cancer and four with lower ureteral cancer performed laparoscopy-assisted total nephroureterectomy from May 1997 to December 2000 (Ten males and one female, mean age 68.5 year-old). METHOD: Of the 11 patients, the initial one received preoperative embolization of the renal artery. Under general anesthesia laparoscopy-assisted total nephroureterectomy underwent via transperitoneal approach in three patients and retroperitoneal approach in eight. After the kidney was completely dissected under laparoscopic procedure, it was delivered en bloc with ureter from the skin incision in the lower abdomen. RESULT: Two patients needed conversion to open surgery. The mean operating time of nine patients except for conversion cases was 272 minutes and the mean blood loss was 313 ml. There was no major complication associated with laparoscopic procedure. There was no significant difference in both complication and recurrence rate between laparoscopy-assisted total nephroureterectomy and open surgery. CONCLUSION: Laparoscopy-assisted total nephroureterectomy is an useful procedure for the treatment of patients with renal pelvic and lower ureteral cancer because it enables us to remove out the kidney and ureter from one small lower abdominal incision.

5
UI - 21160523
AU - Yamamoto S; Sasaguri T; Shimizu Y; Watanabe J; Shibata KR; Iwasaki R
TI - Renal pelvic carcinoma of horseshoe kidney caused systemic metastasis by implantation in prostate.
SO - Int J Urol 2001 Apr;8(4):184-7
AD - Department of Urology, Hamamatsu Rosai Hospital, Hamamatsu, Japan. shingoy@kuhp.kyoto-u.ac.jp
A case is reported of renal pelvic carcinoma of the horseshoe kidney in a 69-year-old man, which showed an interesting metastatic pattern by implantation in the prostate. A few months after transurethral resection of the prostate for benign prostate hyperplasia and extracorporal shock wave lithotripsy for renal stones, the patient complained of severe back pain due to multiple metastatic bone tumors. Autopsy revealed transitional cell carcinoma in the pelvis as well as in the prostate with remarkable vessel invasion. The clinical course and autopsy findings suggested that the systemic expansion of cancer cells from the renal pelvis was caused not only by direct metastasis but also by implantation in the prostate.

6
UI - 21294369
AU - el Khader K; Ouali M; Koutani A; Attya AI; Hachimi M; Lakrissa A
TI - [Transitional cell carcinoma on ureteral stump after nephrectomy for pyonephrosis]
SO - Prog Urol 2001 Apr;11(2):304-6
AD - Service d'Urologie B, Hopital Avicenne, Rabat, Maroc. elkhader.k@yahoo.fr
The authors report a case of transitional cell carcinoma of the left ureteral stump in a 66-year old man treated by nephrectomy for pyonephrosis 6 years previously and cystoprostatectomy for bladder tumour 13 years previously. In the light of this case and based on a review of the literature, they essentially discuss the diagnostic and aetiopathogenic problems raised by this disease.