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Tipos de C�ncer > Veterinario de OncoLink > Oncología Veterinaria > Tumores
Apocrine Gland Tumors
Supported by the Savannah and Barry French Poodle Memorial Fund
Affiliation:
University of Pennsylvania School of Veterinary Medicine
Ultima Vez Modificado: 21 de agosto del 2005
Michael H. Goldschmidt, MSc, BVMS, MRCVS, Diplomate ACVP Professor and Head, Laboratory of Pathology and Toxicology Chief, Surgical Pathology Department of Pathobiology
Frances S. Shofer, PhD, Adjunct Associate Professor of Epidemiology and Biostatistics
Introduction
Apocrine glands have both a secretory and a ductal component. The secretion empties into the infundibulum of the hair follicle (epitrichial). The cells that make the secretion are columnar with copious granular eosinophilic cytoplasm and the nuclei are located in the base of the cell. The secretion is produced when the apical portion (top) of the cell is cleaved into the glandular lumen. The secretory cells are surrounded by myoepithelial cells which are surrounded by the basal lamina zone. The apocrine duct is lined by cuboidal epithelial cells that form a double layer.
- Apocrine Adenoma
- Apocrine Ductal Adenoma
- Complex & Mixed Apocrine Adenoma
- Apocrine Carcinoma
- Apocrine Ductal Carcinoma
- Complex & Mixed Apocrine Carcinoma
- References
Apocrine Adenoma
Definition: A benign tumor with differentiation to apocrine secretory epithelium.
Epidemiology
| Sex | N | Percent |
| Female |
278
|
17% (21%)
|
| Female Spayed |
574
|
35% (33%)
|
| Male |
463
|
28% (25%)
|
| Male Castrated |
331
|
20% (21%)
|
| (Normal Population %) |
| Breeds at Increased Risk |
N | Probability | OR | 95% Confidence Interval |
|
| Peekapoo |
15
|
<0.0001
|
4.7
|
2.8
|
7.8
|
| Alaskan Malamute |
11
|
0.0024
|
2.8
|
1.6
|
5.2
|
| Chow Chow |
17
|
0.0004
|
2.7
|
1.6
|
4.3
|
| Lhasa Apso |
45
|
<0.0001
|
2.6
|
1.9
|
3.5
|
| Old English Sheepdog |
20
|
0.0002
|
2.6
|
1.6
|
4.0
|
| Shih Tzu |
44
|
0.0003
|
1.8
|
1.4
|
2.5
|
| Collie |
23
|
0.0196
|
1.7
|
1.1
|
2.6
|
| Golden Retriever |
162
|
<0.0001
|
1.4
|
1.2
|
1.7
|
| Breeds at Decreased Risk |
N | Probability | OR | 95% Confidence Interval |
|
| Boxer |
19
|
<0.0001
|
0.39
|
0.25
|
0.62
|
| Miniature Schnauzer |
9
|
0.0011
|
0.38
|
0.20
|
0.73
|
| Doberman Pinscher |
13
|
<0.0001
|
0.28
|
0.16
|
0.48
|
| Boston Terrier |
2
|
0.0161
|
0.22
|
0.06
|
0.89
|
| Shar-Pei |
2
|
0.0059
|
0.20
|
0.05
|
0.79
|
| Pug |
1
|
0.0125
|
0.14
|
0.02
|
1.01
|
| Jack Russell Terrier |
1
|
0.0063
|
0.12
|
0.02
|
0.89
|
| Great Dane |
1
|
0.0003
|
0.09
|
0.01
|
0.61
|
| Apocrine Adenoma & Complex & Mixed Adenoma Site | Percent |
| Head | 21.7% |
| Neck | 19.4% |
| Forelimb | 14.6% |
| Hindlimb | 12.1% |
| Back | 7.2% |
| Abdomen | 7.0% |
| Thorax | 7.0% |
| Tail | 5.8% |
| Perineum | 3.4% |
| Multiple | 1.6% |
| Scrotum | 0.3% |
