Jacqui Tan, MD
OncoLink Assistant Editor
Ultima Vez Modificado: 1 de noviembre del 2001
Presenter: LM Freedman
Affiliation: University of Texas M.D. Anderson Cancer Center
Breast cancers associated with a genetic predisposition (e.g., BRCA-1 & BRCA-2 mutations) may behave more aggressively than sporadically occurring tumors. In particular, they tend to present at higher grades, lack hormone receptors, and have mutations of other genes such as p53. One might then question whether patients carrying these mutations could be at an increased risk of loco-regional recurrence with breast conserving therapy (BCT).
Because of the unwieldy cost and effort to identify the small percentage (<10%) of patients at risk, a diagnosis of bilateral breast cancer with a positive family history was used as a surrogate for germline mutations. These patients were assessed for loco-regional recurrence rates with BCT.
ASTRO coverage is sponsored, in part, by Varian Medical Systems, Inc.Imprima English
Apr 25, 2011 - Comprehensive smoke-free policies among U.S. states increased dramatically between 2000 and 2010, making the Healthy People 2020 target of all states having comprehensive smoke-free policies achievable with continued efforts and accelerated efforts in the Southern states, according a report in the April 22 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
Apr 25, 2011
Jun 8, 2011