New Chemotherapy and Biotherapeutic Agents - Post Test

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  1. In which of the following years were the most new chemotherapy / biotherapy agents FDA approved?
    1. 2004
    2. 2012
    3. 2009
    4. 2011

  2. Ado-trastuzumab emtansine (Kadcyla) is a type of __________ used to treat HER2 positive breast cancer.
    1. Immune therapy
    2. Hormonal therapy
    3. Monoclonal antibody with a cytotoxic drug conjugate
    4. None of the above

  3. Due to the risk of embryo-fetal toxicity, pomalidomide is only available through a restricted program called Pomalyst REMS, which requires the following:
    1. Female patients must comply with pregnancy testing.
    2. All patients must comply with contraception requirements.
    3. Prescribers and Pharmacies must be certified with REMS.
    4. All of the above

  4. When administering carfilzomib, the following are necessary:
    1. Pre and Post Hydration
    2. Monitor for infusion reaction
    3. Give dexamethasone premedication prior to all cycle 1 doses and first cycle 2 dose
    4. All of the above

  5. You should inform patients who are taking bosutinib that:
    1. They should not eat grapefruit or drink grapefruit juice.
    2. They can take proton pump inhibitors for reflux symptoms.
    3. They should not take antacids for 1 hour before or 2 hours after taking the medication.
    4. A & C

  6. All of the following medications were approved for CML in 2012, except:
    1. Ponatinib (Iclusig)
    2. Bosutinib (Bosulif)
    3. Dasatinib (Sprycel)
    4. Omacetaxine (Synribo)

  7. When counseling a patient taking cabozantinib, you should tell them:
    1. The total dose is 140mg is made up of 1-80mg and 3-20mg capsules.
    2. They could experience changes in hair color.
    3. Do not eat for at least 2 hours before and 1 hour after each dose.
    4. All of the above

  8. When taking regorafenib, the manufacturer recommends that patients take it with a low-fat breakfast.
    1. True
    2. False

  9. Vincristine Liposomal (Marqibo) preparation:
    1. Requires a controlled temperature water bath.
    2. It can be prepared by the patient at home.
    3. Is labor and time intensive for the pharmacist to prepare.
    4. A & C

  10. Nurses play a critical role in educating patients regarding their medications, including:
    1. How to take their medications (i.e. with/without food, foods to avoid).
    2. Safety surrounding home administration of oral agents.
    3. Importance of adherence and what to do if a dose is missed.
    4. All of the above

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