Nursing Management of Chemotherapy-Induced Peripheral Neuropathy - Post Test

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1. Neuropathy
1. Is an irritation or damage to the nerves.
2. Can affect sensory, motor and autonomic nerves.
3. Can be caused by certain chemotherapy agents.
4. All of the above.
2. The pathophysiology of CIPN is unknown, but theories include nerve damage through excitotoxicity or a dying back of the nerves.
1. True
2. False
3. Risk factors for CIPN include:
1. Patient’s medical history of renal failure
2. Receiving treatment with vincristine
3. The patient plays golf daily
4. A & B
4. Prior to starting therapy with a potentially neurotoxic agent, a baseline neurologic exam including muscle strength, sensory ability and reflexes should be performed.
1. True
2. False
5. Symptoms of CIPN can include:
1. Weakness in extremities
2. Tripping
3. Difficulty buttoning a shirt
4. All of the above
6. There are no proven treatments for CIPN, partially because of the lack of understanding of the pathophysiology behind this side effect.
1. True
2. False
7. Calcium and Magnesium infusions:
1. Have had success in reducing CIPN rates when used preventively.
2. Is thought to work by increasing ion concentration outside the cells and, in turn, decreasing the frequency of sodium channel openings.
3. Require further research to determine effectiveness with various chemotherapy agents and optimal doses.
4. All of the above
8. Tricyclic antidepressants work by inhibiting the re-uptake of norepinepherine and serotonin, which are both thought to decrease nerve excitability.
1. True
2. False
9. Medications being studied or used to treat CIPN include:
1. Glutamine
2. Opiods
3. Pregabalin
4. All of the above
10. Patient education for the patient with CIPN should include:
1. The importance of reporting worsening or changing symptoms.
2. Methods to improve safety in the home.
3. Symptoms often improve 6-12 months after treatment, but can become chronic for some.
4. All of the above

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