Walter AW, ... Kun LE
Abramson Cancer Center of the University of Pennsylvania
Ultima Vez Modificado: 1 de noviembre del 2001
Reviewers: John Han-Chih Chang, MD
Source: Journal of Clinical Oncology 1998; Volume 16: pages 3761 - 67.
The St. Jude Total Therapy Program is a series of protocols utilized on childhood ALL patients from 1967 - 1988. The data regarding secondary brain tumors are summarized above and this corroborates other reported series.1-3 There seems to be a definite association of secondary brain tumors with cranial irradiation and RT dose, but no significant correlation with intrathecal chemotherapy. As a result of this and other series, only select high risk ALL patients receive cranial irradiation along with intrathecal chemotherapy.
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