CLL Prognosis

Ultima Vez Modificado: 8 de enero del 2006

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Question

Dear OncoLink "Ask The Experts,"

I am a 48-year-old male recently diagnosed with CLL ( chronic lymphocytic leukemia ). My white blood cell count is 14.05, my red count is 4.59, and my hemoglobin count is 14.1. I just had a bone marrow biopsy, but have not received the results yet. I am also scheduled for a CT scan.

I am fairly active, I run 3 miles 3 times a week and do resistance training 3-4 times a week. Should I stop exercising and conserve my energy? I am concerned about becoming anemic. What is the general prognosis for CLL patients these days?

Answer

Carolyn Vachani RN, MSN, AOCN, OncoLink's Nurse Educator, responds:

I don't think you should stop exercising unless you feel tired. In general, studies show that even people with anemia have more energy if they do exercise (now, most of the studies were talking about a walk around the block, not your extent of exercise), but as long as you feel well, I see no reason not to stay active.

As far as prognosis, th is varies based on a staging system called the " Rai system for CLL" - it is dependent on any swelling of lymph nodes, splee n, or liver and the presence of anemia and/or low platelet count and high white cell count. The stages range from 0 to I V, but have been simplified to low, intermediate, and high risk.

Rai System for CLL

Simplified Stage

Clinical Features

Median Survival

Low risk

Lymphocytosis (elevated WBC) in blood & bone marrow only

> 12.5 years

Intermediate Risk

Lymphocytosis + lymphadenopathys (enlarged lymph nodes)

8.5 years

  Splenomegaly or hepatomegaly (enlarged spleen or liver) 6 years

High risk

Lymphocytosis, anemia & thrombocytopenia (low platelet count)

1.5-4 years

Many patients with CLL can go on for years without treatment, and be managed with just regular monitoring of blood counts. It all depends on the aggressiveness of that person's disease.

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