Información sobre riesgo, prevención, detección, síntomas, diagnosis, tratamiento y apoyo para el cáncer.
Información sobre el tratamiento del cáncer incluyendo quirúrgica, quimioterapia, radioterapia, estudios clínicos, terapia con protón, medicina complementaria avanzadas.
OncoLink se complace en ofrecer una amplia lista de lista completa de los agentes quimioterapéuticos más comúnmente usados??. Esta guía de referencia incluye información sobre la forma en que cada fármaco se administra, cómo funcionan, y los pacientes los efectos secundarios comunes pueden experimentar.
Maneras que los pacientes de cáncer y las personas que le cuidan puedan enfrentar el cáncer, los efectos secundarios, nutrición, cuestiones en general sobre el apoyo para el cáncer, duelo/decisiones sobre el termino de vida, y experiencias compartidas por sobrevivientes.
Eric Shinohara, MD, MSCI
Ultima Vez Modificado: 7 de agosto del 2008
Dear OncoLink "Ask The Experts,"
I would like your opinion regarding the risk/benefit of proton beam radiotherapy vs. conventional radiotherapy in a patient with a low-risk cancer status-post radical prostatectomy who now has rising PSA levels (biochemical failure) without any imaging evidence of recurrent tumor- hence, suspected local recurrence. Is there really less morbidity to proton beam therapy, without compromise in efficacy?
Eric Shinohara, MD, MSCI Radiation Oncology Section Editor for OncoLink responds;
The major advantage of protons is that the area being treated with radiation can be specifically targeted while sparing the surrounding normal tissues, thanks to unique properties of the proton beam. Learn more about the differences between proton therapy and photon therapy (3-D conformal and IMRT Radiation) in this article. Sparing of normal tissue may be important when a tumor is near critical normal tissues that cannot tolerate high doses of radiation. There are ongoing studies evaluating protons for treatment of prostate cancer.
However, in a man who has already had a radical prostatectomy and now has a recurrence, the entire area where the prostate gland was located needs to be treated. Because the bladder and rectum fall into the hole where the prostate gland was previously located, there is no way to spare these structures from radiation by using protons.
There may be a reduced risk of secondary cancers due to radiation when protons are used because they spread less radiation dose to normal tissues. However, this is theoretical, and most models available at present suggest that a special type of proton beam, known as a scanning beam, would be best at reducing dose to normal tissues. Unfortunately, this beam is not yet widely available.
Hence, at present there is not a clear benefit to protons (and for that matter IMRT) in the treatment of recurrent prostate cancer after prostatectomy over 3D conformal radiation therapy.
Ms. Gambino talks about the complexity of cancer care and the need for patients and families to have help in navigating from diagnosis and treatment decisions to survivorship. Read more.
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