Treatment Options for Metastatic Gastric Cancer

Li Liu, MD
Ultima Vez Modificado: 1 de noviembre del 2001

Share article


Question
I have a 33 year-old sister who has developed stage IV gastric cancer. The cancer was discovered last May 1999 and 85% of her stomach was cut out and 3/15 lymph nodes were positive. Recently, the cancer has come back outside of her stomach and has metastasized to her liver. Can you point me to any clinical trials?


Answer
Li Liu, MD, OncoLink Editorial Assistant, responds:

Dear P,  
Thank you for your interest and question.

The standard care for patients with metastatic gastric cancer has been 5-FU-based chemotherapy. Some small randomized studies have demonstrated the survival advantage of 5-FU based chemotherapy plus supportive care over supportive care alone (Semin Oncol 1996 Jun;23(3):397-406). Some newer combination chemotherapy regimens have shown very high response rates. Unfortunately, the chance of cure for patients with advanced gastric cancer is low. New cytotoxic agents currently under investigation for advanced gastric cancer include irenotecan, taxol, gemcitabine, oxaliplatin, UFT, endostatin, and some immunotherapy agents.

Numerous clinical trials testing these agents and other treatments are available, either national or in some local medical centers. You can search active clinical trials through CancerNet, which is sponsored by National Cancer Institute.


News
ASCO: Regorafenib Improves Survival in Metastatic CRC

Jan 20, 2012 - For patients with metastatic colorectal cancer that has progressed after standard therapies, treatment with regorafenib significantly improves overall survival and progression-free survival compared with placebo, according to a study presented at the American Society of Clinical Oncology's annual Gastrointestinal Cancers Symposium, held from Jan. 19 to 21 in San Francisco.



I Wish You Knew

How cancer patients have changed my life

View More



Blogs and Web Chats

OncoLink Blogs give our readers a chance to react to and comment on key cancer news topics and provides a forum for OncoLink Experts and readers to share opinions and learn from each other.




OncoLink OncoPilot

Frente a un nuevo diagnóstico de cáncer o de cambiar el curso de su tratamiento actual? Deje que nuestro personal de enfermería cáncer que ayudan a pasar!

Más información