OncoLink Cancer Treatment and Resources
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Neutropenia


Improving the Management of Chemotherapy-Induced Neutropenia: Progress in Developing Once-per-Cycle Cytokine Support
Presenter: Jeffrey Crawford, MD Chemotherapy induced neutropenia is one of the primary dose limiting toxicities of cancer treatment, putting patients at risk of infection and frequently leading to treatment interruptions and sub-optimal chemotherapy or radiotherapy dosing. Daily filgrastim is a widely used agent to reduce the clinical impact of

Development and Validation of the FACT-Neutropenia
Presenter: Elizabeth A. Calhoun Presenter's Affiliation: Northwestern University Background The Functional Assessment of Cancer Therapy (FACT)is a series of validated scales designed to measure quality of life (QOL). It consists of a general measure (FACT-G) and specific subscales related to the effects of the disease, its symptoms, and

The Epidemiology and Economics of Neutropenia in Hospitalized Adult Cancer Patients: Data From the University HealthSystem Consortium
Presenter: Gary H. Lyman Presenter's Affiliation: Albany Medical College Type of Session: Poster Background Neutropenia is a common toxicity of conventional chemotherapy accounting for a large percentage of inpatient hospital expenditures, particularly when neutropenia related fever results. Febrile neutropenia patients generally require

Neutropenia Control: Optimising Therapeutic Gains
Neutropenia is often the dose limiting toxicity in chemotherapy treatment. A great advance came with filgrastin, decreasing the incidence of febrile neutropenia and hospitalizations in patients given the injections following chemotherapy. The use of filgrastin, however, requires daily injections which can be inconvenient or even impossible for

Cigarette smoking during irinotecan therapy: Effects on pharmacokinetics and neutropenia
Scientific Session: Cigarette smoking during irinotecan therapy: Effects on pharmacokinetics and neutropenia Cytochrome P450 enzymes in the liver are important for the detoxification of many drugs and substances. Exposure to cigarette smoke can affect the expression of cytochrome P450 enzymes and has been demonstrated to affect the levels and

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