Andrea Branas, MSE, MPT, CLT & Joy Cohn, PT, DPT, CLT
Good Shepherd Penn Partners
Ultima Vez Modificado: 12 de diciembre del 2011
Lymphedema is a chronic swelling that happens when lymph fluid is not moving well and protein-rich fluid accumulates in the tissues. It is non-painful and is not life threatening.
The lymph system consists of lymph nodes and vessels. The lymph vessels run parallel to the blood vessels. The lymph system helps to manage fluid volume and fight disease. Lymph nodes and vessels drain excess fluid from the entire body and return it to the blood near the heart. Lymph nodes filter viruses, dying cells, foreign matter, and bacteria to fight infection. The lymph system also recycles proteins through the body. Lymphedema develops slowly unless there is trauma or infection to the area of the body where your lymph nodes and vessels are not working.
In some cases, people inherit or are born with a poorly working lymph system. This is called primary lymphedema. Lymphedema can also occur as a result of damage, such as trauma, surgery or radiation for cancer treatment, to the lymph nodes or lymph vessels. Damaged leg veins or a history of blood clots can cause a back up of blood and fluid in the small vessels of the body and progress to the lymph system. These are all causes of secondary lymphedema.
Your risk for developing lymphedema increases with the greater the number of lymph nodes removed, receiving radiation therapy, being overweight, having active cancer, or having an infection/injury to the body part at risk for swelling. Not all swelling in the body is lymphedema. Be sure to discuss swelling anywhere in your body with your physician/nurse or therapist, even if the swelling comes and goes. For more information on lymphedema risk, see the article on risk reduction for lymphedema. Learn more about lymphedema risk reduction.
Signs of lymphedema development include slow progression of swelling, which typically begins at the far end of your limb (hands and feet) and then moves up the arm or leg. Skin can be pitting (when a finger is pressed into the area the indentation remains.) In stage I, this swelling may reduce with elevation. In stage II and III lymphedema, there is progressive hardening of the tissues in the affected area. With increased protein-rich swelling, there is a risk for bacterial growth and infection.
Skin changes may occur with the development of lymphedema. Local infections, often called "cellulitis," may cause the limb to become red, hot, painful and swollen. This infection can spread quickly, so early diagnosis and treatment is the key to keeping the infection and swelling under control.
Lymphedema can be pitting or non-pitting edema (swelling). Pitting edema is present when a mark is left in the skin by applying finger pressure. This is often seen with a recent accumulation of fluid and protein.
Hyperkeratosis and papillomas may also be seen in someone with lymphedema. Hyperkeratosis is an overgrowth of the skin like a very thick callus. Papillomas are raised wart-like growths that can appear on the skin of people with longstanding lymphedema.
Your medical history is the key to the diagnosis of lymphedema. Your physician will look at your history from cancer diagnosis to treatment along with any past surgeries or medical history. These factors will be used to help determine your risk for lymphedema
Physicians will use clinical and diagnostic tools to determine a specific diagnosis of lymphedema. Some of these tests are also used to rule out other causes of swelling.
When these tests are negative for other causes, the patient history and physical examination are usually sufficient to make the diagnosis of lymphedema
Specific tests of the lymphatic system are usually reserved for cases where the diagnosis is unclear or if more specific information about the lymphatic structure is necessary. Diagnostic tests may include lymphoscintigraphy, ultrasound, CT or MRI. Lymphoscintigraphy is a nuclear medicine test where an agent is injected into the lymphatic system. This fluid is then followed as it is carried through the body and is used to determine the structure and function of the lymphatics. Ultrasound can visualize enlarged lymph nodes. Computerized tomography (CT) scans are useful to look for soft tissue growths in the lymph nodes or to determine metastatic disease.
There are 3 stages of lymphedema based on how long the fluid has been in the body part and what type of changes are seen as a result of the fluid. In Stage I, there is very little swelling. The swelling that does exist may come and go. At this stage, the lymphedema is said to be reversible. There may be times when there is NO swelling.
In Stage II, there is considerably more swelling, because the fluid is the tissues. In this stage, there is obvious swelling of the limb. The skin may feel tighter and may be shiny. The tissue may also feel thick and firm to the touch; the tissue may form pits when pressed. These changes are caused by scar tissue, or fibrosis, beginning to form. The fluid CAN be moved out of the tissue, but it won't happen without help from the outside.
Stage III lymphedema is a severe and prolonged accumulation of edema or swelling in the body part. The skin can become hardened with a leathery feel. The color of the skin can become darker with a brownish tint. There may also be papillomas of the skin, which are small bumps that form on the skin and may leak fluid. This stage is termed Lymphostatic elephantiasis. It is not possible for the body to clear the fluid on its own. Even with intense therapy, this fluid is difficult to remove. However, since the skin is such a dynamic organ, tissue changes and softening may be seen with treatment. Learn more about lymphedema treatment.
National Lymphedema Network: 1-800-541-3259
Check the Position Papers for information on a variety of lymphedema related topics.
American Cancer Society: 1-800-ACS-2345
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