OncoLink at ASCO 2000: Saturday, May 20 | Oncolink

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A clinical trial comparing concurrent Cisplatin and radiation therapy versus radiation alone for locally advanced Squamous Cell Carcinoma of the cervix carried out by the National Cancer Institute of Canada Clinical Trials Group Presenter: Gavin Stuart Affiliation: NCI Canada, University of Alberta, Edmonton, Canada, others Background: In 1999, multiple abstracts of phase III trials comparing chemoradiation with radiation alone in localized cervix cancer were...
A Multi-Center Study of the Costs of Enrolling Cancer Patients on Phase II Clinical Trials Presenter: T.J. Stinson Affiliation: Northwestern University Background: It has long been assumed by health insurance companies that clinical trial costs are much larger than those incurred in standard practice. For this reason, both medicare...
A Phase II Study (GOG 153) of Recurrent and Advanced Endometrial Carcinoma Treated with Alternating Courses of Megestrol Acetate and Tamoxifen Citrate Presenter: James V. Fiorica Affiliation: H. Lee Moffitt Cancer Center, others Background: Progestins are commonly used in the treatment of endometrial cancer, but downregOLation of progesterone receptors may shorten response duration. ...
A Phase III Comparison of Standard Radiation Therapy (RT) Versus RT Plus Concurrent Cisplatin (CDDP) Versus Split-Course RT Plus ConcurrentCDDPP and 5-Flourouracil (5-FU) in Patients with Unresectable Squamous Cell Head and Neck Cancer (SCHNC): An Intergroup Study Presenter: DJ Adelstein Affiliation: ECOG & SWOG Background: Unresectable squamous cell carcinoma of the head and neck region conotates a very poor prognosis overall. Recent Phase II trials have suggested the addition of concurrent...
A Phase III Randomized Trial Comparing Concurrent Chemotherapy-Radiotherapy with Radiotherapy Alone in Locoregionally Advanced Nasopharyngeal Carcinoma Presenter: A.T. Chan Affiliation: Chinese University Hospital of Hong Kong, and others. Background: Nasopharyngeal carcinoma (NPC) has been shown to be highly responsive to chemoradiation. The intergroup trial 0099 (Al-Sarraf, et al) showed a...
Alternating Chemo-Radiotherapy Versus Partly Accelerated Radiotherapy in Advanced Squamous Cell Carcinoma of the Head and Neck: Results of a Phase III Randomized Trial Presenter: M. Benasso Affiliation: Inst Nazionale per la Ricera sul Cancro and affiliated centers, Genoa, Italy Background: It has previously been shown that alternating chemo-radiotherapy (ALT) has improved outcome compared with conventional...
Clinical Trial Costs Are Similar To and May be Less Than Standard Care and Inpatient (INPT) Charges at an Academic Medical Center (AMC) are Similar to Major, Minor and Non-Teaching Hospitals Presenter: J. Quirk Affiliation: Memorial Sloan-Kettering Cancer Center Background: Payers limit access to medical centers where clinical trials are performed. Insurance companies and Medicare have not facilitated treatment in clinical trials...
Effective First Line Therapy of Ovarian Cancer with Cisplatin and Prolonged Topotecan Infusion - A NYGOG/ECOG Study Presenter: J. Speyer Affiliation: Mt. Sinai Sch of Med, NYU Sch of Med, Albert Einstein Sch of Med Background: Becuase of the known activity of cisplatin and topotecan as second line treatment of ovarian cancer and the favorable results with a...
Phase III Comparison of Sequential vs Concurrent Chemoradiation for Patients (Pts) with Unresected Stage III Non-Small Cell Lung Cancer (NSCLC): Initial Report of Radiation Therapy Oncology Group (RTOG) 9410. Presenter: Walter Curran Affiliation: Bodine Ctr for Cancer Treatment Background: Radiation therapy with or without chemotherapy is standard therapy for locally advanced unresectable non-small cell lung cancer (NSCLC) The use of...
Preliminary Results of Intergroup INT 0123 Randomized Trial of Combined Modality Therapy (CMT) for Esophagel Cancer: Standard vs. High Dose Radiation Therapy Presenter: B.D. Minsky Affiliation: RTOG, ECOG, NCCTG, others Background: Although definitive chemoradiation for esophageal cancer is a relatively good treatment option for patients with non-metastatic disease, survival rates remain...