OncoLink Cancer Treatment and Resources

Patient Summary: Adjuvant chemotherapy in stage IB non-small cell lung cancer (NSCLC): Update of Cancer and Leukemia Group B (CALGB) protocol 9633
Adjuvant chemotherapy in stage IB non-small cell lung cancer (NSCLC): Update of Cancer and Leukemia Group B (CALGB) protocol 9633. The CALGB 9633 trial randomized patients with stage IB non small cell lung cancer NSCLC to either...
Patient Summary: Adjuvant radiotherapy (RT) and trastuzumab in stage I-IIA breast cancer: Toxicity data from North Central Cancer Treatment Group Phase III trial N9831
Adjuvant radiotherapy (RT) and trastuzumab in stage I-IIA breast cancer: Toxicity data from North Central Cancer Treatment Group Phase III trial N9831 NCCTG N9831 is a 3-arm randomized Phase III trial involving stage I-IIA breast cancer patients...
Patient Summary: Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clinical trials including 4,584 patients
Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clinical trials including 4,584 patients This study pooled the results (also called meta-analysis) of multiple studies of non small cell lung cancer treated with...
Patient Summary: Motexafin gadolinium (MGd) combined with prompt whole brain radiation therapy (RT) prolongs time to neurologic progression in non-small cell lung cancer (NSCLC) patients with brain metastases: Results of a phase III trial
Adjuvant chemotherapy in elderly patients: An analysis of National Cancer Institute of Canada Clinical Trials Group and Intergroup BR.10 There have been several studies showing the benefit of chemotherapy in surgically resected non small cell lung...
Patient Summary: Outcome of clear cell sarcoma of the kidney (CCSK) treated on the National Wilms Tumor Study-5 (NWTS)
Outcome of clear cell sarcoma of the kidney (CCSK) treated on the National Wilms Tumor Study-5 (NWTS) Clear cell sarcoma of the kidney was first described in the 1970's and has a tendency to metastasize to the bone and can relapse long after...
Patient Summary: Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alpha (IFN-alpha) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC)
Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alpha (IFN-alpha) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC). This study looked at one of the recently approved drugs for renal...
Patient Summary: Phase III trial of intermittent MAB vs continuous MAB
Phase III trial of intermittent MAB vs continuous MAB This trial began with 766 patients with locally advanced or metastatic prostate cancer. These men were initially treated with three months of therapy consisting of 2 weeks of 200mg cyproterone...
Patient Summary: Predicting the outcome of salvage radiotherapy for recurrent prostate cancer after radical prostatectomy
Predicting the outcome of salvage radiotherapy for recurrent prostate cancer after radical prostatectomy When a patient has a rising PSA after radical prostatectomy, they are often recommended hormone therapy, but this is not without side effects....
Patient Summary: Randomized phase III trial comparing induction chemotherapy using cisplatin (P) fluorouracil (F) with or without docetaxel (T) for organ preservation in hypopharynx and larynx cancer. Preliminary results of GORTEC 2000-01
Randomized phase III trial comparing induction chemotherapy using cisplatin (P) fluorouracil (F) with or without docetaxel (T) for organ preservation in hypopharynx and larynx cancer. Preliminary results of GORTEC 2000-01 Chemotherapy followed by...
Patient Summary: Randomized phase III trial of capecitabine/cisplatin (XP) vs. continuous infusion of 5FU/cisplatin (FP) as first line therapy in patients (pts) with advanced gastric cancer (AGC): Efficacy and safety results
Randomized phase III trial of capecitabine/cisplatin (XP) vs. continuous infusion of 5FU/cisplatin (FP) as first line therapy in patients (pts) with advanced gastric cancer (AGC): Efficacy and safety results. This study looked to prove that Xeloda...
Patient Summary: Superiority of trimodality therapy to surgery alone in esophageal cancer: Results of CALGB 9781
Superiority of trimodality therapy to surgery alone in esophageal cancer: Results of CALGB 9781 There is some controversy over the best treatment for surgically resectable esophageal cancer , so this study looked to compare surgery alone to...
Patient Summary: The study of tamoxifen and raloxifene (STAR): Initial findings from the NSABP P-2 breast cancer prevention study
The study of tamoxifen and raloxifene (STAR): Initial findings from the NSABP P-2 breast cancer prevention study The STAR trial included post-menopausal women with a high risk of developing breast cancer (Gail model risk 1.66%). Women were...
Patient Summary: The Women's Health Initiative randomized trial of calcium plus vitamin D: Effects on breast cancer and arthralgias
The Women's Health Initiative randomized trial of calcium plus vitamin D: Effects on breast cancer and arthralgias. This study looked at the question: would calcium and vitamin D supplements decrease risk of breast cancer ? 32,282 women were...
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