OncoLink at ASTRO 1999: Monday November 1 | Oncolink

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3-D Intensity Modulated Radiotherapy (IMRT) in the Treatment of Nasopharyngeal Carcinoma: The UCSF Experience Presenter: Khalil Sultanem, MD Affiliation: University of California (San Francisco) Summary:Due to the proximity of critical normal tissues, carcinoma of the nasopharynx requires technically complex radiation treatment planning. The nasopharynx...
A Radiation Therapy Oncology Group (RTOG) Phase III Randomized Study to Compare Hyperfractionation and Two Variants of Accelerated Fractionation to Standard Fractionation Radiotherapy for Head and Neck Squamous Cell Carcinomas: Preliminary Results of RTOG Presenter: Karen K. Fu, MD Affiliation: RTOG and University of California San Francisco Summary:Various fractionation schemes have been advocated for the treatment of head and neck cancer based on single institution experiences. This...
Accuracy of the Extent of Axillary Nodal Positivity Related to Primary Tumor Size, Number of Involved Nodes and Number of Nodes Examined Presenter: Rajesh V Iyer, MD Affiliation: Fox Chase Cancer Center Background:As radiation therapy's utility becomes more established in the breast conservation and post-mastectomy setting, the issue of axillary lymph node status remains in the...
Can We Predict Radiation (RT)-Induced Changes in Pulmonary Function Tests (PFTs) Based on the Lung Dose-Volume Histogram? Presenter: Ming Fan, M.D. Affiliation: Duke University Medical Center Summary: Radiation induced pulmonary changes can cause serious, even life-threatening problems in patients whose lung function is already compromised by tumor burden and...
Chemoprevention for Head and Neck Cancer "Can chemopreventive therapy restore molecular defects in target tissues?" That was the key question posed by Dr. Wang Ki Hong, Chair of Thoracic Oncology at the University of Texas M.D. Anderson Cancer Center, in his keynote address to a packed...
Circulating Humoral Factors and Lymphocyte Subsets as Markers for Radiation Pulmonary Injury Presenter: Yuhchyau Chen, M.D. Affiliation: University of Rochester Summary:Radiation induced pulmonary changes can cause serious, even life-threatening problems in patients whose lung function my already be compromised by tumor burden and/or...
Energy and intensity modulated electron beams for treatment of breast cancer Presenter: Charles Ma Affiliation: Stanford University School of Medicine Summary:Breast cancer has traditionaly been treated with photon beams. The purpose of this study was to investigate the feasibility of using energy and intensity...
Extracapsular Axillary Nodal Extension (ECE) in Breast Cancer: Patterns of Recurrence, Arm Edema, and Survival after Mastectomy with and Without Irradiation Presenter: Robert Kuske, MD Affiliation: Ochsner Clinic/Tulane University School of Medicine, New Orleans, LA Background:The prognostic implications of extracapsular extension (ECE) in breast cancer with axillary lymph node (ALN) disease is...
Final Report of a Phase III Randomized Trial of Amifostine as a Radioprotectant in Head and Neck Cancer Presenter: Brizel DM et al Affiliation: Duke University Medical Center Summary:Xerostomia (dry mouth) is a difficult and often permanent complication of head and neck radiotherapy. Life long consequences include difficulty with eating,...
Impact of Hemoglobin (Hgb) Level and Use of Recombinant Human Erythropoieten (r-HuEPO) on Response to Neoadjuvant Chemoradiation Therapy, Tumor Control, and Survival in Patients With Oral or Oropharyngeal Squamous Cell Carcinoma (SCCA) Presenter: Christoph M. Glaser, MD Affiliation: General Hospital Vienna, Austria Summary:Anemia is a frequent finding in patients with head and neck cancer and has been found to be a poor prognostic factor. This study was performed to evaluate...
Improved Conformality and Reduced Toxicity with High-Dose Intensity Modulated Radiation Therapy (IMRT) for Patients with Prostate Cancer Presenter: Michael J. Zelefsky, M.D. Affiliation: Memorial Sloan Kettering Cancer Center Summary: There has been recent evidence to suggest that with increased radiation dose comes increased efficacy in the treatment of prostate cancer. ...
Intensity modulated stereotactic radiosurgery using a micro-multileaf compared with gamma knife and linac arc radiosurgery Presenter: Wu QJ Affiliation: Case Western Reserve University Summary:Stereotactic radiosurgery is delivered with the use of gamma knife or linac based photon beams. Both of these modalities can provide an acceptable dose distribution. ...
Internal Mammary Node Coverage - An Investigation of Presently-Accepted Techniques Presenter: Douglas Arthur, MD Affiliation: Virginia Commonwealth University/Medical College of Virginia Background:The Internal mammary nodes (IMNs) are found lateral to the internal mammary vessels from the 1st rib to the 4th intercostal space. ...
Internal Mammary Node Irradiation Does Not Decrease Distant Metastases or Improve Survival in Stages I and II Breast Cancer Presenter: Barbara Fowble, MD Affiliation: Fox Chase Cancer Center Background:Internal mammary node (IMN) irradiation has remained a controversial subject. Though historical data demonstrate that high-risk patients (axillary lymph node positive)...
Long Term Results of Immediate Adjuvant Hormonal Therapy with Goserelin in Patients with Locally Advanced Prostate Cancer Treated with Radiotherapy (Phase III EORTC Study) Presenter: Bolla M et al Affiliation: EORTC Radiotherapy Cooperative Group Summary:Traditionally, patients with locally advanced, high risk adenocarcinoma of the prostate have been treated with radiation therapy. However, local control and...
Panel Discusses the Rapidly Evolving Standards of Care for Cervix Cancer In February 1999, the National Cancer Institute issued a clinical alert stating that concurrent cisplatin-based chemotherapy plus radiation therapy appears to be a superior treatment to radiation alone for women with cervix cancer. This statement...
PET Scanning in Radical Radiation Therapy Candidates with Non-Small Cell Lung Cancer: High Impact on Staging and Management and Delineation of a Subgroup with Poor Survival Presenter: Mac Manus MP Affiliation: Peter MacCallum Cancer Institute Summary:The standard work-up for a patient with non-small cell lung cancer (NSCLC) includes surgical staging as well as imaging by CT, bone scan, and possibly MRI. Even in the...
Prelimimary results of a randomized dose-escalation study comparing 70 Gy to 78 Gy for the treatment of prostate cancer Presenter: Alan Pollack Affiliation: MD Anderson Cancer Center Summary:- The purpose of this study was to compare the impact of 70 Gy versus 78 Gy on relapsing/rising PSA and biopsy positivity. Methods: 298 patients were enrolled in a single...
Preliminary Results of Gamma-I Trial, Multi-institution Double Blind Prospective Randomized Study Evaluating the Efficacy of IR-192 to Reduce Coronary In-stent Restenosis Presenter: Prabhakar Tripuraneni, M.D. Affiliation: Scripps Clinic Summary: One of the major disadvantages of coronary angioplasty is the high rate of re-stenosis in the months following the procedure. Single arm endovascular brachytherapy...
Radiation Therapy With Concurrent Weekly Carboplatin and Paclitaxol in Advanced Stage Unresectable Squamous Cell Carcinoma of the Head and Neck Presenter: Michael L. Haas, MD Affiliation: University of Maryland Summary:Advanced squamous cell carcinoma of the head and neck region generally has a poor outcome with radiation therapy alone. This study was designed to evaluate concurrent...
Randomized Phase III Trial of Radiation +/- Amifostine in Patients with Advanced Stage Lung Cancer Presenter: Antonadou D Affiliation: Hellenic Group Clinical-Radiation Oncology, Greece Summary:Pneumonitis and esophagitis are two of the most problematic adverse effects associated with thoracic irradiation. Severe symptoms can cause patient...
Randomized Prospective Comparison of Adjuvant Mediastinal Radiation (RT) with or without Concurrent Chemotherapy with Cisplatin and Etoposide (PE) for Patients with Completely Resected T1-3N1-2M0 Non-Small Cell Lung Cancer (NSCLC): US Presenter: Keller SM et al Affiliation: Beth Israel Medical Center Summary:Multiple retrospective reviews as well as the prospective study from the Lung Cancer Study Group have demonstrated a local control advantage to adjuvant radiation therapy...